4-(Trifluoromethyl)benzoyl chloride → HCID 22147888, compound

Participants

Reaction Steps

Compounds of this invention with Formula VI may be prepared as illustrated by the exemplary reaction in Scheme 6. Reaction of 3-chloro-thiophene-2-carboxylic acid hydrazide with 4-trifluoromethylbenzoyl chloride produces N-(3-chloro-thiophene-2-carbonyl)-N′-(4-trifluoromethylbenzoyl)-hydrazine, followed by treating with thionyl chloride produces 5-(3-chloro-2-thienyl)-3-(4-trifluoromethylbenzoyl)-[1,3,4]-oxadiazole.

Provenance & Evidence