Iodoethane → 6-Ethyl-5,6-dihydro-7H-cyclopenta[b]pyridin-7-one

HRID 1824168Notes

Reaction equation

[CH3:1][CH:2]1[C:10](=[O:11])[C:6]2[CH:7]=[CH:8]S[C:5]=2[CH2:4][CH2:3]1.[N:12]1C=CC=C2C(=O)CC[C:13]=12.ICC>>[CH2:7]([CH:6]1[C:10](=[O:11])[C:13]2=[N:12][CH:1]=[CH:2][CH:3]=[C:4]2[CH2:5]1)[CH3:8]

Participants

Reactant 3

HCID 6340Iodoethane

HCID 15125216,7-Dihydro-5H-1-pyridin-5-one

HCID 154115085-methyl-6,7-dihydro-1-benzothiophen-4(5H)-one

Product 1

HCID 221474816-Ethyl-5,6-dihydro-7H-cyclopenta[b]pyridin-7-one

Procedure

Following the procedure for the preparation of 5-methyl-6,7-dihydro-1-benzothiophen-4(5H)-one but substituting 6,7-dihydro-5H-cyclopenta[b]pyridin-5-one and iodoethane, and making non-critical variations provided the title compound as a oil:

Sources & evidence

ORD record: ord-da1065b1eec348a6bb935d14df44258e
Source dataset: uspto-grants-2006_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07041672B2

Reaction notes

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