反应详情

温度

140 °C

570 mg of trans-1,4-diaminocyclohexane are heated to its melting point 70° C., 290 mg of the product obtained in stage 1 above are added and the medium is then heated at approximately 140° C. for about 4 hours and then left overnight at room temperature. After purification by chromatography on silica with, as eluent, a mixture of CH2Cl2:MeOH:NH4OH (75:22:3) 93 mg of the expected product are obtained in the form of a beige crumbly foam.

1. additionabove are added
2. customAfter purification by chromatography on silica with, as eluent
3. additiona mixture of CH2Cl2:MeOH:NH4OH (75:22:3) 93 mg of the expected product
4. customare obtained in the form of a beige crumbly foam