N,N-dimethyl-p-phenylenediamine → HCID 178482853, compound

HRID 1824470Notes

Reaction equation

HRID 1824470 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([NH:6][CH:7]=[N:8]2)=[C:4](Cl)[N:3]=1.[CH3:12][N:13]([CH3:21])[C:14]1[CH:19]=[CH:18][C:17]([NH2:20])=[CH:16][CH:15]=1>C(O)CCC>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][NH:8]2)=[C:4]([NH:20][C:17]2[CH:18]=[CH:19][C:14]([N:13]([CH3:21])[CH3:12])=[CH:15][CH:16]=2)[N:3]=1

Participants

4

Reactant 2

HCID 7472N,N-dimethyl-p-phenylenediamineHCID 53244122,6-Dichloropurine

Product 1

HCID 178482853HCID 178482853, compoundYield 85.5%

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

The procedure is carried out as in Example 1, starting with 378 mg of 2,6-dichloropurine, 5 ml of butanol and 300 mg of N,N-dimethyl-p-phenylenediamine. 494 mg of the expected product are thus obtained.

Sources & evidence

ORD record
ord-4a83482c0a3b4530b75aa6825a71a15c
Source dataset
uspto-grants-2006_05
Patent number
US07041824B2

Reaction notes

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