反应详情

A mixture of the product of Step A (1.48 g) and 1,4-cyclohexadiene (6.2 mL) and palladium (10% wt on activated carbon) (1.4 g) in ethanol (100 mL) was stirred at reflux temperature for 2 hours and cooled to ambient temperature and stirred for 12 hours. The reaction mixture was filtered through a pad of celite and the celite pad rinsed with ethanol (100 mL) and methanol (100 mL). The filtrate was collected and evaporated to yield the title compound (710 mg).

1. temperatureat reflux temperature for 2 hours
2. stirringstirred for 12 hours
3. filtrationThe reaction mixture was filtered through a pad of celite
4. washthe celite pad rinsed with ethanol (100 mL) and methanol (100 mL)
5. customThe filtrate was collected
6. customevaporated