N,N-Dimethylethylenediamine → HCID 22141709, compound

HRID 1824649Notes

Reaction equation

HRID 1824649 reaction equation
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([O:11][CH3:12])[N:3]=1.[CH3:13][N:14]([CH3:18])[CH2:15][CH2:16][NH2:17]>C(O)C>[CH3:12][O:11][C:4]1[N:3]=[C:2]([NH:17][CH2:16][CH2:15][N:14]([CH3:18])[CH3:13])[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 27950292-Chloro-6-methoxy-3-nitropyridine

Product 1

HCID 22141709HCID 22141709, compoundYield 79.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4 g (0.0212 mol) of the product 2-chloro-3-nitro-6-methoxypyridine, 40 ml of ethanol and 3.85 ml (0.0424 mol) of N,N-dimethylethylenediamine are placed in a fully equipped round-bottomed flask. The mixture is refluxed for 2 hours with stirring and is then poured onto an ice/water mixture with stirring. The precipitate formed is filtered off by suction and dried under vacuum to constant weight. 54.027 g of yellow powder are obtained, ie a yield of 79.1%.

Workup

  1. temperatureThe mixture is refluxed for 2 hours
  2. stirringwith stirring
  3. customThe precipitate formed
  4. filtrationis filtered off by suction
  5. customdried under vacuum to constant weight

Sources & evidence

ORD record
ord-d233759f50ff4f5e84b2d9660db91284
Source dataset
uspto-grants-2006_05
Patent number
US07044987B2

Reaction notes

Loading…