Methyl Acrylate → HCID 69780647, compound

HRID 1824901Notes

Reaction equation

HRID 1824901 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]([C:13]1[CH:18]=[CH:17][C:16](OS(C(F)(F)F)(=O)=O)=[CH:15][CH:14]=1)[CH:8]([C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)[CH2:7][CH2:6]2.[C:33]([O:37][CH3:38])(=[O:36])[CH:34]=[CH2:35]>CC#N>[CH3:38][O:37][C:33](=[O:36])[CH:34]=[CH:35][C:16]1[CH:15]=[CH:14][C:13]([CH:9]2[C:10]3[C:5](=[CH:4][C:3]([O:2][CH3:1])=[CH:12][CH:11]=3)[CH2:6][CH2:7][CH:8]2[C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[CH:18][CH:17]=1

Participants

4

Reactant 2

HCID 7294Methyl AcrylateHCID 53725155HCID 53725155, compound

Product 1

HCID 69780647HCID 69780647, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Prepared by Heck coupling 6c and methyl acrylate in accordance with the general method described in Example IV. Yield (83%); APcI m/z: 440 (M+H+CH3CN+, 100%).

Workup

  1. customPrepared by Heck
  2. customYield (83%)

Sources & evidence

ORD record
ord-26a883231d8c41b29b22b4879ce8707b
Source dataset
uspto-grants-2006_05
Patent number
US07045540B2

Reaction notes

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