Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1824981Generated: November 2, 2026

Hydrochloric Acid → HCID 22144673, compound

https://huagongshe.com/reaction/1824981

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 23573458HCID 23573458—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 22144673HCID 22144673—

Reaction Steps

121 mg (0.20 mmol) of tert-butyl-4-[({1-(2-fluorobenzyl)-5-[(tetrahydro-2H-pyran-4-ylacetyl)amino]-1H-indol-2-yl}carbonyl)amino]phenylcarbamate from Example XXXIII, 1.40 ml of dioxane and 1.40 ml of conc. hydrochloric acid are combined and stirred at RT for one hour. The mixture is evaporated to dryness using a rotary evaporator.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07045544B2
Source datasetuspto-grants-2006_05
ORD IDord-e333b5be9bfc4f38beb2c7b5a9538fc7
Source noteuspto-grants-2006_05