HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 22144673, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 23573458 | HCID 23573458 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 22144673 | HCID 22144673 | — |
Reaction Steps
121 mg (0.20 mmol) of tert-butyl-4-[({1-(2-fluorobenzyl)-5-[(tetrahydro-2H-pyran-4-ylacetyl)amino]-1H-indol-2-yl}carbonyl)amino]phenylcarbamate from Example XXXIII, 1.40 ml of dioxane and 1.40 ml of conc. hydrochloric acid are combined and stirred at RT for one hour. The mixture is evaporated to dryness using a rotary evaporator.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07045544B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-e333b5be9bfc4f38beb2c7b5a9538fc7 |
| Source note | uspto-grants-2006_05 |