Hydrochloric Acid → HCID 69593507, compound

Participants

Reaction Steps

(R)-[2-Hydroxy-1-(3-morpholin-4-ylmethyl-phenyl)-ethyl]-carbamic acid tert-butyl ester (2.1 g, 6.25 mmol) in methanol (22 mL) was added hydrochloric acid (2.0M in ethyl ether) (10.88 mL, 21.8 mmol) and reaction mixture was stirred at room temperature for 5 hr. The reaction mixture was concentrated under vacuum to provide the title compound as a pale green solid (quantitative yield).

Provenance & Evidence