Hydrazine hydrate (1:1) → HCID 69637152, compound

HRID 1825739Notes

Reaction equation

HRID 1825739 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]=[C:11]2[C:16](=[O:17])[NH:15][C:14]3[CH:18]=[CH:19][CH:20]=[CH:21][C:13]=3[O:12]2)=[CH:6][CH:5]=1)([O-])=O.O.NN>[Ni].C(O)C>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([CH:10]=[C:11]2[C:16](=[O:17])[NH:15][C:14]3[CH:18]=[CH:19][CH:20]=[CH:21][C:13]=3[O:12]2)=[CH:8][CH:9]=1

Participants

5

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 57249238HCID 57249238, compound

Product 1

HCID 69637152HCID 69637152, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

A catalytic amount of Raney nickel was added portionwise with stirring to a mixture of 2-[(4-nitrophenyl)methylene]-2H-1,4-benzoxazin-3(4H)-one (0.57 g, 0.002 mol) and hydrazine hydrate (1 ml) in ethanol (20 ml). The reaction mixture was refluxed for 3 h, then filtered. The filtrate was evaporated to dryness under reduced pressure. The crude product was purified by re crystallization from ethanol.

Workup

  1. temperatureThe reaction mixture was refluxed for 3 h
  2. filtrationfiltered
  3. customThe filtrate was evaporated to dryness under reduced pressure
  4. customThe crude product was purified by re crystallization from ethanol

Sources & evidence

ORD record
ord-a4692cad5bee416892c7832e91ff43a3
Source dataset
uspto-grants-2006_05
Patent number
US07049312B1

Reaction notes

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