4,5-Dichloro-1,2-phenylenediamine → HCID 131725761, compound

HRID 1825906Notes

Reaction equation

HRID 1825906 reaction equation
[CH3:1][C:2]1[C:3]([N:7]=[C:8]=S)=[CH:4][S:5][CH:6]=1.[Cl:10][C:11]1[C:16]([Cl:17])=[CH:15][C:14]([NH2:18])=[C:13]([NH2:19])[CH:12]=1>>[ClH:10].[Cl:10][C:11]1[C:16]([Cl:17])=[CH:15][C:14]2[N:18]=[C:8]([NH:7][C:3]3[C:2]([CH3:1])=[CH:6][S:5][CH:4]=3)[NH:19][C:13]=2[CH:12]=1

Participants

3

Reactant 2

HCID 792974,5-Dichloro-1,2-phenylenediamineHCID 221398273-Isothiocyanato-4-methylthiophene

Product 1

HCID 131725761HCID 131725761, compound

Procedure

N-(2-Amino-4,5-dichlorophenyl)-N′-(4-methyl-3-thienyl)thiourea is obtained analogously to the reaction described in example 1b) from 4-methyl-3-thienyl isothiocyanate and 4,5-dichloro-1,2-diaminobenzene. Crystalline solid, m.p. 310-320° C. b) 3N-(5,6-Dichloro-2-benzimidazolyl)-4-methyl-3-thienylamine hydrochloride is obtained analogously to the procedure described in example 1c) from N-(2-amino-4,5-dichlorophenyl)-N′-(4-methyl-3-thienyl)thiourea and methyl iodide.

Sources & evidence

ORD record
ord-b86b5f042d9b4fba8f267ecd8a945210
Source dataset
uspto-grants-2006_05
Patent number
US07049333B2

Reaction notes

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