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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1826591Generated: October 31, 2026

tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate → HCID 23577081, compound

https://huagongshe.com/reaction/1826591

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylateHCID 11011301—
ReactantEthyl acetate hexaneHCID 21226206—
ReactantHCID 86587672HCID 86587672—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 23577081HCID 2357708116%

Reaction Steps

A solution of the product of Example 12 and the product of Example 129 in dioxane is heated under reflux for 1.5 hours. The reaction is poured into hexane/ethyl acetate (1:1), and the solid is collected. Flash chromatography using dichloromethane as eluant gave 0.08 g (16%) of the product as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07053070B2
Source datasetuspto-grants-2006_05
ORD IDord-3ac00313c06e45ccb9d75740e48c6c17
Source noteuspto-grants-2006_05