HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-formyl-5-methyl-1H-pyrrole-3-carboxylic acid → 5-Methyl-2-(2-oxo-4-piperidin-4-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-formyl-5-methyl-1H-pyrrole-3-carboxylic acid | HCID 21915588 | — |
| Reactant | 4-(Piperidin-4-yl)indolin-2-one | HCID 22135396 | — |
| Product | 5-Methyl-2-(2-oxo-4-piperidin-4-yl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid | HCID 69584181 | — |
Reaction Steps
4-Piperidin-4-yl-1,3-dihydroindol-2-one (45 mg, 0.2 mmol) was condensed with 2-formyl-5-methyl-1H-pyrrole-3-carboxylic acid (34 mg, 0.23 mmol) to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053086B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-542c6bf75bcf423c977bb6657e3de2f2 |
| Source note | uspto-grants-2006_05 |