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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1826784Generated: October 31, 2026

4-(Piperidin-4-yl)indolin-2-one → HCID 69584198, compound

https://huagongshe.com/reaction/1826784

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Piperidin-4-yl)indolin-2-oneHCID 22135396—
ReactantHCID 86586558HCID 86586558—
CatalystPiperidineHCID 8082—
SolventEthanolHCID 702—
ProductHCID 69584198HCID 69584198—

Reaction Steps

A mixture of 4-piperidin-4-yl-1,3-dihydroindol-2-one (35.6 mg, 0.165 mmol), 5-formyl-4-methyl-1H-pyrrole-3-carboxylic acid [3-(2-oxo-pyrrolidin-1-yl)propyl]-amide (48 mg, 0.173 mmol) and piperidine (2 drops) in ethanol (0.5 mL) was stirred at room temperature for 7 days. The reaction was concentrated and ether was added to the residue. The precipitate which formed was collected by vacuum filtration, washed with ethanol and ether and dried to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07053086B2
Source datasetuspto-grants-2006_05
ORD IDord-beb661d55a2847c39c74dd1865e80134
Source noteuspto-grants-2006_05