HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Piperidin-4-yl)indolin-2-one → HCID 69584198, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Piperidin-4-yl)indolin-2-one | HCID 22135396 | — |
| Reactant | HCID 86586558 | HCID 86586558 | — |
| Catalyst | Piperidine | HCID 8082 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 69584198 | HCID 69584198 | — |
Reaction Steps
A mixture of 4-piperidin-4-yl-1,3-dihydroindol-2-one (35.6 mg, 0.165 mmol), 5-formyl-4-methyl-1H-pyrrole-3-carboxylic acid [3-(2-oxo-pyrrolidin-1-yl)propyl]-amide (48 mg, 0.173 mmol) and piperidine (2 drops) in ethanol (0.5 mL) was stirred at room temperature for 7 days. The reaction was concentrated and ether was added to the residue. The precipitate which formed was collected by vacuum filtration, washed with ethanol and ether and dried to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053086B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-beb661d55a2847c39c74dd1865e80134 |
| Source note | uspto-grants-2006_05 |