Pyridine → HCID 22136421, compound

HRID 1826875Notes

Reaction equation

HRID 1826875 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=[CH:3][C:2]=1[C:11](Cl)=[O:12].[C:14]12([OH:24])[CH2:23][CH:18]3[CH2:19][CH:20]([CH2:22][CH:16]([CH2:17]3)[CH2:15]1)[CH2:21]2.N1C=CC=CC=1>O>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=[CH:3][C:2]=1[C:11]([O:24][C:14]12[CH2:21][CH:20]3[CH2:19][CH:18]([CH2:17][CH:16]([CH2:22]3)[CH2:15]1)[CH2:23]2)=[O:12]

Participants

5

Reactant 3

HCID 1049PyridineHCID 641521-AdamantanolHCID 2734681Quinoxaline-2-carbonyl chloride

Product 1

HCID 22136421HCID 22136421, compoundYield 16.6%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Prepared from 2-quinoxaloyl chloride (0.84 g, 4.4 mmol), 1-adamantanol (0.60 g, 3.9 mmol), pyridine (10 mL), and water (100 mL) yielding 0.20 g (16%) of (92):

Sources & evidence

ORD record
ord-67e5f7f642aa4672be12b63002ef784b
Source dataset
uspto-grants-2006_05
Patent number
US07053104B2

Reaction notes

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