2,3-Dimethylcyclohexylamine → HCID 22136401, compound

HRID 1826896Notes

Reaction equation

HRID 1826896 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=[CH:3][C:2]=1[C:11](Cl)=[O:12].[CH3:14][CH:15]1[CH:20]([CH3:21])[CH2:19][CH2:18][CH2:17][CH:16]1[NH2:22]>N1C=CC=CC=1>[CH3:14][CH:15]1[CH:20]([CH3:21])[CH2:19][CH2:18][CH2:17][CH:16]1[NH:22][C:11]([C:2]1[CH:3]=[N:4][C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[N:1]=1)=[O:12]

Participants

4

Reactant 2

HCID 1235072,3-DimethylcyclohexylamineHCID 2734681Quinoxaline-2-carbonyl chloride

Product 1

HCID 22136401HCID 22136401, compoundYield 59%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Prepared from 2-quinoxaloyl chloride (193 mg, 1.0 mmol), 2,3-dimethylcyclohexylamine (115 mg, 0.90 mmol), and pyridine (5 mL) yielding 150 mg (59%) of (163): rt=10.12 min.; m/z (rel. int.) 283 (M+, 35), 212 (6), 198 (14), 175 (6), 174 (39), 158 (7), 157 (22), 131 (6), 130 (46), 129 (100), 126 (44), 109 (8), 103 (20), 103 (20), 102 (45), 76 (13), 75 (11), 67 (7), 56 (10), 55 (12), 51 (6), 43 (6), 41 (16).

Sources & evidence

ORD record
ord-4e85c1aa695944f0b9d4e0c6f900bffc
Source dataset
uspto-grants-2006_05
Patent number
US07053104B2

Reaction notes

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