Hydrochloric Acid → 2-Aminomethyl-3-bromo-benzoic acid hydrochloride salt

Participants

Reaction Steps

A mixture of 2-(tert-Butoxy carbonylamino-methyl)-3-bromo-benzoic acid (0.188 g, 0.57 mmol) in 2M HCl in diethyl ether (10 ml) was stirred at room temperature for 18 hours. The solvent was removed by evaporation under reduced pressure. The solid was diluted with ethyl acetate/dioxan (1:1) (10 ml) and stirred at room temperature for 1.5 hours. The solid was filtered off and dried to give the title compound (0.02 g, 13%) as a white solid.

Provenance & Evidence