反应详情

A mixture of 2-(tert-Butoxy carbonylamino-methyl)-3-bromo-benzoic acid (0.188 g, 0.57 mmol) in 2M HCl in diethyl ether (10 ml) was stirred at room temperature for 18 hours. The solvent was removed by evaporation under reduced pressure. The solid was diluted with ethyl acetate/dioxan (1:1) (10 ml) and stirred at room temperature for 1.5 hours. The solid was filtered off and dried to give the title compound (0.02 g, 13%) as a white solid.

1. customThe solvent was removed by evaporation under reduced pressure
2. additionThe solid was diluted with ethyl acetate/dioxan (1:1) (10 ml)
3. stirringstirred at room temperature for 1.5 hours
4. filtrationThe solid was filtered off
5. customdried