HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyrimidine → Benzyl 4-[(2-pyrimidinylamino)methyl]-1-piperidinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyrimidine | HCID 74404 | — |
| Reactant | 4-Aminomethyl-1-N-Cbz-piperidine | HCID 21955499 | — |
| Product | Benzyl 4-[(2-pyrimidinylamino)methyl]-1-piperidinecarboxylate | HCID 9923385 | — |
Reaction Steps
The title compound was prepared as described in EXAMPLE 13, except using benzyl 4-(aminomethyl)-1-piperidinecarboxylate (6.50 g, 26.19 mmol) and 2-chloropyrimidine (990 mg, 8.64 mmol) as starting materials without a solvent to give the title compound as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053089B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-0b34ae9c11784acba231fe44a95fe1ba |
| Source note | uspto-grants-2006_05 |