HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23577242, compound → (5-Methyl-pyrimidin-4-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23577242 | HCID 23577242 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | EtOH triethylamine | HCID 22663003 | — |
| Product | (5-Methyl-pyrimidin-4-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amine | HCID 23577256 | — |
Reaction Steps
EXAMPLE 92 was prepared from (2-chloro-5-methyl-pyrimidin-4-yl)-[1-(2-phenyl-ethanesulfonyl)-piperidin-4-ylmethyl]-amine by hydrogenation in ethanol-triethylamine over 5% palladium on carbon, 1 atm of hydrogen: MS (m+1)=375.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053089B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-f810b440943a4ee8be4db80353bb3f77 |
| Source note | uspto-grants-2006_05 |