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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1827245Generated: October 31, 2026

Trifluoroacetic acid → Trifluoroacetate

https://huagongshe.com/reaction/1827245

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 58635339HCID 58635339—
SolventDichloromethaneHCID 6344—
ProductTrifluoroacetateHCID 84468—
ProductHCID 58635332HCID 58635332—

Reaction Steps

A solution of tert-butyl (1-{[(1R,2R)-2-phenylcyclopropyl]carbonyl}piperidin-4-yl)methylcarbamate (1.00 g, 2.79 mmol) in TFA (3 mL) and CH2Cl2 (3 mL) was stirred at R.T. for 0.5 h. The reaction mixture was then concentrated to give the title compound as a trifluoroacetate salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07053089B2
Source datasetuspto-grants-2006_05
ORD IDord-22137ea8beca4eb68c637e5c925a4b41
Source noteuspto-grants-2006_05