HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 58635339 | HCID 58635339 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Trifluoroacetate | HCID 84468 | — |
| Product | HCID 58635332 | HCID 58635332 | — |
Reaction Steps
A solution of tert-butyl (1-{[(1R,2R)-2-phenylcyclopropyl]carbonyl}piperidin-4-yl)methylcarbamate (1.00 g, 2.79 mmol) in TFA (3 mL) and CH2Cl2 (3 mL) was stirred at R.T. for 0.5 h. The reaction mixture was then concentrated to give the title compound as a trifluoroacetate salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07053089B2 |
| Source dataset | uspto-grants-2006_05 |
| ORD ID | ord-22137ea8beca4eb68c637e5c925a4b41 |
| Source note | uspto-grants-2006_05 |