Ammonium Hydroxide → HCID 22137910, compound

HRID 1827368Notes

Reaction equation

C([O:3][C:4](=O)[C:5]([CH3:25])([CH3:24])[C:6]([NH:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([F:23])[CH:18]=2)=[CH:11][CH:10]=1)=[O:7])C.[OH-].[NH4+:28]>>[F:23][C:19]1[CH:18]=[C:17]([CH:22]=[CH:21][CH:20]=1)[CH2:16][O:15][C:12]1[CH:13]=[CH:14][C:9]([NH:8][C:6](=[O:7])[C:5]([CH3:25])([CH3:24])[C:4]([NH2:28])=[O:3])=[CH:10][CH:11]=1

Participants

Reactant 2

HCID 14923Ammonium Hydroxide

HCID 69007672HCID 69007672, compound

Product 1

HCID 22137910HCID 22137910, compound

Procedure

The title compound is prepared in analogy to example 3 from N-[4-(3-fluoro-benzyloxy)-phenyl]-2,2-dimethyl-malonamic acid ethyl ester and ammonium hydroxide. Colorless solid. MS: m/e=331.4 (M++H).

Sources & evidence

ORD record: ord-d77460e1c2bb4e74bbdeb5488f19c961
Source dataset: uspto-grants-2006_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07053245B2

Reaction notes

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