Ammonium Hydroxide → HCID 9996107, compound

HRID 1827372Notes

Reaction equation

HRID 1827372 reaction equation
C[O:2][C:3](=O)[CH2:4][C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[CH:17]=2)=[C:10]([F:23])[CH:9]=1)=[O:6].[OH-].[NH4+:26]>>[F:23][C:10]1[CH:9]=[C:8]([NH:7][C:5](=[O:6])[CH2:4][C:3]([NH2:26])=[O:2])[CH:13]=[CH:12][C:11]=1[O:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[CH:17]=1

Participants

3

Reactant 2

HCID 14923Ammonium HydroxideHCID 9974187HCID 9974187, compound

Product 1

HCID 9996107HCID 9996107, compound

Procedure

The title compound is prepared in analogy to example 3 from N-[3-fluoro-4-(3-fluoro-benzyloxy)-phenyl]-malonamic acid methyl ester and ammonium hydroxide. Light yellow solid. MS: m/e=321.2 (M++H).

Sources & evidence

ORD record
ord-72ce946b31564d828f47f1d759d26b9c
Source dataset
uspto-grants-2006_05
Patent number
US07053245B2

Reaction notes

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