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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1827374Generated: October 31, 2026

1-Fluoro-4-[(4-nitrophenoxy)methyl]benzene → 4-(4-Fluoro-benzyloxy)-phenylamine

https://huagongshe.com/reaction/1827374

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Fluoro-4-[(4-nitrophenoxy)methyl]benzeneHCID 957511—
Reactant4-(3-Fluoro-benzyloxy)-phenylamineHCID 16775314—
Product4-(4-Fluoro-benzyloxy)-phenylamineHCID 6486021100%

Reaction Steps

Prepared in analogy to 4-(3-fluoro-benzyloxy)-phenylamine, by hydrogenation of 4-(4-fluoro-benzyloxy)-nitrobenzene. Yield: 100% of a slightly red solid. MS: m/e=218.2 (M++H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07053245B2
Source datasetuspto-grants-2006_05
ORD IDord-e361d08a8dcb474f8c761cfcb8e7ab64
Source noteuspto-grants-2006_05