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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1827389Generated: November 1, 2026

1-(Aminocarbonyl)-1-cyclopropanecarboxylic acid → Cyclopropane-1,1-dicarboxylic acid amide [4-(3-fluoro-phenoxymethyl)-phenyl]-amide

https://huagongshe.com/reaction/1827389

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Aminocarbonyl)-1-cyclopropanecarboxylic acidHCID 2733272—
Reactant4-(3-Fluoro-phenoxymethyl)-phenylamineHCID 16793806—
ProductCyclopropane-1,1-dicarboxylic acid amide [4-(3-fluoro-phenoxymethyl)-phenyl]-amideHCID 13172450742%

Reaction Steps

The title compound is prepared in analogy to example 2 from 4-(3-Fluoro-phenoxymethyl)-phenylamine and 1-(aminocarbonyl)-1-cyclopropane-carboxylic acid. Yield=42%. Colorless solid. MS: m/e=329.3 (M++H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07053245B2
Source datasetuspto-grants-2006_05
ORD IDord-0497a65e14d24afba27b753ef36f789b
Source noteuspto-grants-2006_05