Ammonium Hydroxide → HCID 22137886, compound

HRID 1827398Notes

Reaction equation

HRID 1827398 reaction equation
C[O:2][C:3](=O)[CH2:4][C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([S:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[CH:17]=2)=[CH:10][CH:9]=1)=[O:6].[OH-].[NH4+:25]>>[F:22][C:18]1[CH:17]=[C:16]([CH:21]=[CH:20][CH:19]=1)[CH2:15][S:14][C:11]1[CH:12]=[CH:13][C:8]([NH:7][C:5](=[O:6])[CH2:4][C:3]([NH2:25])=[O:2])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 14923Ammonium HydroxideHCID 69010945HCID 69010945, compound

Product 1

HCID 22137886HCID 22137886, compoundYield 47%

Procedure

Prepared in analogy to example 3 from N-[4-(3-fluoro-benzylsulfanyl)-phenyl]-malonamic acid methyl ester and ammonium hydroxide. Yield=47%. Colorless solid. MS: m/e=319.3 (M++H).

Sources & evidence

ORD record
ord-5cff55ce425c4763abbdcd35b5f985bd
Source dataset
uspto-grants-2006_05
Patent number
US07053245B2

Reaction notes

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