Ammonium Hydroxide → HCID 10088477, compound

HRID 1827403Notes

Reaction equation

HRID 1827403 reaction equation
C[O:2][C:3](=O)[CH2:4][C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][C:16]2[CH:21]=[C:20]([F:22])[C:19]([F:23])=[CH:18][C:17]=2[F:24])=[CH:10][CH:9]=1)=[O:6].[OH-].[NH4+:27]>>[F:24][C:17]1[CH:18]=[C:19]([F:23])[C:20]([F:22])=[CH:21][C:16]=1[CH2:15][O:14][C:11]1[CH:12]=[CH:13][C:8]([NH:7][C:5](=[O:6])[CH2:4][C:3]([NH2:27])=[O:2])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 14923Ammonium HydroxideHCID 10089404HCID 10089404, compound

Product 1

HCID 10088477HCID 10088477, compoundYield 52%

Procedure

Prepared in analogy to example 3 from N-[4-(2,4,5-trifluoro-benzyloxy)-phenyl]-malonamic acid methyl ester and ammonium hydroxide. Yield=52%. Colorless solid. MS: m/e=339.2 (M++H).

Sources & evidence

ORD record
ord-78c901831d7244af90538be94036efc5
Source dataset
uspto-grants-2006_05
Patent number
US07053245B2

Reaction notes

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