2-Methylallylamine → HCID 69353414, compound

Participants

Reaction Steps

Prepared in a similar manner to that described for Example 6 above, except using 2-Methyl-allylamine and 2-[3-[2-(4-Methyl-pyridin-2-yl)-vinyl]-1-(tetrahydro-pyran-2-yl)-1H-indazol-6-ylamino]-benzoic acid. 1H NMR (DMSO-d6) δ 9.86 (1H, s), 8.81 (1H, t, J=5.5 Hz), 8.46 (1H, d, J=4.9 Hz), 8.07 (1H, d, J=8.9 Hz), 7.86 (1H, d, J=16.4 Hz), 7.75 (1H, d, J=7.7 Hz), 7.54 (1H, s),7.50 (1H, d, J=16.4 Hz), 7.43 (3H, m), 7.11 (2H, m), 6.92 (1H, t, J=8.1 Hz), 5.81 (1H, dd, J=2.5, 9.8 Hz), 4.83 (2H, d, J=11.5 Hz), 3.81 (4H, m), 2.41 (1H, m), 2.35 (3H, s), 2.00 (2H, m), 1.76 (1H, m), 1.73 (3H, s), 1.58 (2H, m). Anal. Calcd for C31H33N5O2.0.80 TBME: C, 72.71; H, 7.43; N, 12.11. Found: C, 72.43; H, 7.57; N, 12.02.

Provenance & Evidence