反应详情

N-[(2,4-Diaminopteridin-6-yl)methyl]carbazole (Formula I: Ar=2,4-diaminopteridin-6-yl; W=CH2; X=N; Z=chemical bond; m=n=0) is prepared similarly to N-(2,4-diaminopteridin-6-yl)methyl-N,N-diphenylamine as disclosed above by using carbazole (129 mg, 0.77 mmol), NaH (50 mg, 2.1 mmol), and 2,4-diamino-6-bromomethylpteridine hydrobromide (100 mg, 0.3 mmol). The product can be purified by chromatography.

1. customThe product can be purified by chromatography