Hydrochloric Acid → HCID 22063500, compound

HRID 1827759Notes

Reaction equation

HRID 1827759 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10]([NH:13]C=O)([CH3:12])[CH3:11].Cl>>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10]([NH2:13])([CH3:11])[CH3:12]

Participants

3

Procedure

Reaction of 22.0 g (100 mmol) of N-[2-(2,4-difluorophenyl]-1,1-dimethylethyl]formamide analogously to the method for Example 10(c). Yield: 16.0 g (72%, hydrochloride); melting point: 201° C.–203° C.

Sources & evidence

ORD record
ord-22ec698545804024b95d2d5b5a27becc
Source dataset
uspto-grants-2006_06
Patent number
US07056916B2

Reaction notes

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