HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22091412, compound → HCID 22091413, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22091412 | HCID 22091412 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 22091413 | HCID 22091413 | — |
Reaction Steps
The ester from (a) was dissolved in 10 mL of 4 N HCl in 1,4-dioxane at 0° C. for 1 hour. The solution was concentrated in vacuo and the salt neutralized by sodium bicarbonate solution and the product extracted with CH2Cl2. After concentration of the organic extract, the crude product was purified by reverse-phase HPLC to yield the desired product; MS, m/z 462=M+1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07056915B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-5a55149203ac4077b7b9365b93f6703e |
| Source note | uspto-grants-2006_06 |