化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Carbonate → Methyl benzimidate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Carbonate | HCID 10340 | — |
| 反応物 | Methyl benzimidate hydrochloride | HCID 5743287 | — |
| 溶媒 | Diethyl Ether | HCID 3283 | — |
| 生成物 | Methyl benzimidate | HCID 345018 | 81.4% |
反応手順
Benzimidic acid methyl ester hydrochloride (5 g, 29.1 mmol) was partitioned between saturated sodium carbonate solution (200 mL) and diethyl ether (100 mL). The organic layer was dried (MgSO4) and concentrated to provide the desired product as a colorless liquid (3.20 g, 81%). This material was used without further purification. 1H NMR (400 MHz, CDCl3) δ 3.93 (s, 3H), 7.39–7.46 (m, 3H), 7.75 (d, J=1.1 Hz, 2H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07056915B2 |
| 出典データセット | uspto-grants-2006_06 |
| ORD ID | ord-e5204b29a4354152b23d144db8a2d913 |
| 出典メモ | uspto-grants-2006_06 |