HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl [2-(pyridin-2-yl)ethyl]carbamate → 2-(Boc-2-aminoethyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl [2-(pyridin-2-yl)ethyl]carbamate | HCID 22027815 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-(Boc-2-aminoethyl)piperidine | HCID 5001226 | — |
Reaction Steps
The product from step A was mixed with PtO2 (640 mg) in HOAc (30 mL) and hydrogenation was carried out at 58 psi on a Parr apparatus for overnight. Catalyst was removed and solvent was evaporated under reduced pressure to give N-t-butoxycarbonyl 2-(piperidin-2-yl) ethylamine as a black liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07056937B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-635313394ca24fa39a96735fe4b012e3 |
| Source note | uspto-grants-2006_06 |