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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1828080Generated: October 29, 2026

Ethoxy-(3-pyridin-4-yl-pyrazol-1-yl)-acetic acid → (RS)-[amino-(4-{[2-ethoxy-2-(3-pyridin-4-yl-pyrazol-1-yl)-acetylamino]-methyl}-phenyl)-methylene]-carbamic acid benzyl ester

https://huagongshe.com/reaction/1828080

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthoxy-(3-pyridin-4-yl-pyrazol-1-yl)-acetic acidHCID 22064729—
ReactantCarbamic acid, [[4-(aminomethyl)phenyl]iminomethyl]-, phenylmethyl ester, dihydrochlorideHCID 141089245—
Product(RS)-[amino-(4-{[2-ethoxy-2-(3-pyridin-4-yl-pyrazol-1-yl)-acetylamino]-methyl}-phenyl)-methylene]-carbamic acid benzyl esterHCID 69641596—

Reaction Steps

According to general method C, ethoxy-(3-pyridin-4-yl-pyrazol-1-yl)-acetic acid was reacted with [(4-aminomethyl-phenyl)-imino-methyl]-carbamic acid benzyl ester dihydrochloride (CAS 172348-75-3) to give (RS)-[amino-(4-{[2-ethoxy-2-(3-pyridin-4-yl-pyrazol-1-yl)-acetylamino]-methyl}-phenyl)-methylene]-carbamic acid benzyl ester. White powder. MS 513.3 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07056932B2
Source datasetuspto-grants-2006_06
ORD IDord-efb9188e3b84471bb7dd776cda3e732f
Source noteuspto-grants-2006_06