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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1828091Generated: October 30, 2026

(Rs)-methoxy-[1-(2-trimethylsilanyl-ethoxymethyl)-1h-benzoimidazol-2-yl]-acetic acid → HCID 178496437, compound

https://huagongshe.com/reaction/1828091

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Rs)-methoxy-[1-(2-trimethylsilanyl-ethoxymethyl)-1h-benzoimidazol-2-yl]-acetic acidHCID 22064658—
ReactantCarbamic acid, [[4-(aminomethyl)phenyl]iminomethyl]-, phenylmethyl ester, dihydrochlorideHCID 141089245—
ProductHCID 178496437HCID 178496437—

Reaction Steps

According to general procedure C, (RS)-methoxy-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-benzoimidazol-2-yl]-acetic acid was reacted with [(4-aminomethyl-phenyl)-imino-methyl]-carbamic acid benzyl ester dihydrochloride (CAS 172348-75-3) to give (RS)-[1-amino-1-[4-({2-methoxy-2-[1-(2-trimethylsilanyl-ethoxymethyl)-1H-benzoimidazol-2-yl]-acetylamino}-methyl)-phenyl]-meth-(E)-ylidene]-carbamic acid benzyl ester. Light yellow solid. MS 602.3 ([M+H]+)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07056932B2
Source datasetuspto-grants-2006_06
ORD IDord-3bde4960113b48338554c33031cbb908
Source noteuspto-grants-2006_06