HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1828191Generated: October 30, 2026
Sulfuric acid hydrate (1:1) → HCID 22063879, compound
https://huagongshe.com/reaction/1828191
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sulfuric acid hydrate (1:1) | HCID 21910475 | — |
| Reactant | HCID 22063940 | HCID 22063940 | — |
| Product | HCID 22063879 | HCID 22063879 | — |
Reaction Steps
(1-Cyclobutyl-3-methyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-acetonitrile (11.5 g) was diluted with sulfuric acid:water (1:1, 25 mL) and was heated to 110° C. for 4 hour then cooled and extracted into ethyl acetate, dried over sodium sulfate and concentrated to give 11.99 g of (1-Cyclobutyl-3-methyl-2-oxo-2,3-dihydro-1H-benzoimidazol-5-yl)-acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07056918B2 |
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| Source dataset | uspto-grants-2006_06 |
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| ORD ID | ord-ad8d7748c134485883e7398bd5961c35 |
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| Source note | uspto-grants-2006_06 |
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