HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxy-4-methyl-2-nitropyridine → 2-Pyridinamine,3-methoxy-4-methyl-(9CI)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxy-4-methyl-2-nitropyridine | HCID 14929577 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Pyridinamine,3-methoxy-4-methyl-(9CI) | HCID 22063765 | 103.4% |
Reaction Steps
The 3-methoxy-4-methyl-2-nitropyridine (1 g) obtained in (A) was dissolved in methanol (50 ml), added with 5% Pd/C (200 mg), and stirred at a pressure of 40 psi for 2 hours under hydrogen atmosphere. After the catalyst was removed by filtration, the solvent was evaporated under reduced pressure to obtain the title compound (850 mg) as yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07056917B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-51b8d38c280b4a1b873c80a8120d7d35 |
| Source note | uspto-grants-2006_06 |