Propylamine → HCID 10291371, compound

HRID 1828576Notes

Reaction equation

[CH2:1]([NH2:4])[CH2:2][CH3:3].[CH3:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[N:13]=[C:14]([C:25](O)=[O:26])[N:15]([CH3:24])[C:16]=2[C:17]2[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=2)=[CH:8][CH:7]=1>>[CH2:1]([NH:4][C:25]([C:14]1[N:15]([CH3:24])[C:16]([C:17]2[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=2)=[C:12]([C:9]2[CH:8]=[CH:7][C:6]([CH3:5])=[CH:11][CH:10]=2)[N:13]=1)=[O:26])[CH2:2][CH3:3]

Participants

Reactant 2

HCID 7852Propylamine

HCID 22066080HCID 22066080, compound

Product 1

HCID 10291371HCID 10291371, compound

Procedure

Using essentially the same procedure as Example 9, Step B, but using n-propylamine (0.015 mL), 4,5-di-(4-methylphenyl)-1-methylimidazole-2-carboxylic acid (25 mg, 0.08 mmol) from Example 9, Step A was converted to the title compound. HPLC/MS: 348 (M+1); Rt=3.76 min.

Sources & evidence

ORD record: ord-e58fc5a63f374b2e88c873ba78cedb32
Source dataset: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07057051B2

Reaction notes

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