Sodium Hydroxide → HCID 21028574, compound

Participants

Reaction Steps

2.96 g (10 mmol) XVI and 6.00 g NaOH were heated under reflux for 3.5 h in 100 ml degassed water. The still hot solution was then acidified with concentrated HCl to pH 1. The compound XVII precipitating on cooling in an ice bath was removed and washed with a little n-hexane. A yield of 1.23 g XVII (6.3 mmol, 63%) was obtained.

Provenance & Evidence