Tetraethoxysilane → Bis(pentafluorophenyl)diethoxysilane

HRID 1828678Notes

Reaction equation

HRID 1828678 reaction equation
Br[C:2]1[C:7]([F:8])=[C:6]([F:9])[C:5]([F:10])=[C:4]([F:11])[C:3]=1[F:12].[Mg].C(O[Si:17]([O:24][CH2:25][CH3:26])([O:21][CH2:22][CH3:23])OCC)C>CCOCC>[F:8][C:7]1[C:2]([Si:17]([C:2]2[C:3]([F:12])=[C:4]([F:11])[C:5]([F:10])=[C:6]([F:9])[C:7]=2[F:8])([O:21][CH2:22][CH3:23])[O:24][CH2:25][CH3:26])=[C:3]([F:12])[C:4]([F:11])=[C:5]([F:10])[C:6]=1[F:9]

Participants

5

Reactant 3

HCID 6517TetraethoxysilaneHCID 9578BromopentafluorobenzeneHCID 5462224Magnesium

Product 1

HCID 11102434Bis(pentafluorophenyl)diethoxysilane

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Conditions

Temperature
35 °C

Procedure

265.2 mL (1.95 mol, 525.353 g) bromopentafluorobenzene, 52.11 g (2.144 mol) magnesium powder and 216 mL (0.975 mol, 203.025 g) tetraethoxysilane are mixed together at room temperature and diethylether is added dropwise to the vigorously stirred solution until an exothermic reaction is observed (˜240 mL). The solution is stirred for 30 minutes after which additional 90 mL of Et2O is carefully added. After stirring at 35° C. for 16 h the mixture is cooled to room temperature and diethylether evaporated. An excess of n-heptane (˜600 mL) is added to precipitate the magnesium salts. Solution is filtrated and evaporated to dryness. The residue is fractionally distilled under reduced pressure to yield di(pentafluorophenyl)diethoxysilane.

Workup

  1. additionis carefully added
  2. temperatureis cooled to room temperature
  3. customdiethylether evaporated
  4. additionAn excess of n-heptane (˜600 mL) is added
  5. customto precipitate the magnesium salts
  6. filtrationSolution is filtrated
  7. customevaporated to dryness
  8. distillationThe residue is fractionally distilled under reduced pressure

Sources & evidence

ORD record
ord-31eeab7ed15f464f90241f0ea20b472f
Source dataset
uspto-grants-2006_06
Patent number
US07060634B2

Reaction notes

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