HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 69662367, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5-Methoxyindan-1-one | HCID 78787 | — |
| Reactant | 5-Methyl-3-phenylisoxazole-4-carboxaldehyde | HCID 2776144 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 69662367 | HCID 69662367 | 49% |
Reaction Steps
5-Methoxy-1-indanone (1 g, 6.2 mmol) and 3-phenyl-5-methyl-4-isoxazolecarbaldehyde (1.14 g, 6.2 mmol) were dissolved in EtOH (30 ml) and NaOH(4 drops of a 4M solution in water) was added. The reaction mixture was heated to reflux for 17 h. The reaction mixture was cooled and filtered to obtain the title compound as a yellow solid (1.0 g, 49%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07060710B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-aeed545cf2a2440283b61cd371b3a231 |
| Source note | uspto-grants-2006_06 |