Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Reactant | HCID 14458246 | HCID 14458246 | — |
| Solvent | Ammonia | HCID 222 | — |
| Product | HCID 22059160 | HCID 22059160 | — |
Reaction Steps
A mixture of 3-(ethoxycarbonylmethyl)-2-pyrazolin-5-one (1 g, 5.8 mmol) and NaCN (28 mg, 0.58 mmol) in 30 ml of 9M ammonia in MeOH was heated to 45° C. in sealed tube for 3 days. After cooling, the solvent was evaporated and the residue was suspended in water. The precipitated solid was collected by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07060822B1 |
|---|
| Source dataset | uspto-grants-2006_06 |
|---|
| ORD ID | ord-81f63d4f38e44213b61de7eb31ed8ed3 |
|---|
| Source note | uspto-grants-2006_06 |
|---|
