HCID 11439448, compound → HCID 9968509, compound

HRID 1828958Notes

Reaction equation

HRID 1828958 reaction equation
[C:1]([O:5][C:6]([NH:8][C@@H:9]([CH3:25])[C:10]([N:12]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][C@H:13]1[C:21]([O:23][CH3:24])=[O:22])=[O:11])=[O:7])([CH3:4])([CH3:3])[CH3:2]>CO.[Rh]>[C:1]([O:5][C:6]([NH:8][C@@H:9]([CH3:25])[C:10]([N:12]1[C@@H:20]2[C@@H:15]([CH2:16][CH2:17][CH2:18][CH2:19]2)[CH2:14][C@H:13]1[C:21]([O:23][CH3:24])=[O:22])=[O:11])=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 1

HCID 11439448HCID 11439448, compound

Product 1

HCID 9968509HCID 9968509, compound

Reagents, catalysts & solvents 2

HCID 23948RhodiumCatalystHCID 887MethanolSolvent

Procedure

The residue obtained in Example 1 (1 kg) is dissolved in methanol and transferred to a hydrogenator, and then 0.10 kg of 5% rhodium-on-carbon is added.

Sources & evidence

ORD record
ord-5a902643ab434bd19f494fb095ee854a
Source dataset
uspto-grants-2006_06
Patent number
US07060842B2

Reaction notes

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