反应详情

A solution of 1.1 g (4.92 mmol) of 2A in 10 mL of 48% HBr was heated to reflux under argon atmosphere for 3.5 hours and then concentrated to dryness under reduced pressure. To this was added 50 mL of dichloromethane and concentrated to dryness under reduced pressure to give crude 2B as a dark brown powder (M+Na, 318).

1. temperatureto reflux under argon atmosphere for 3.5 hours
2. concentrationconcentrated to dryness under reduced pressure
3. additionTo this was added 50 mL of dichloromethane
4. concentrationconcentrated to dryness under reduced pressure