反应详情

3-Amino-4-cyanophenol (6.71 g) was dissolved in pyridine (100 mL), and potassium ethylxanthate (8.82 g) was added thereto. The mixture was refluxed for 2 hr. After allowing to cool, iced water (200 mL) was added to the reaction mixture, and conc. hydrochloric acid (40 mL) was added thereto. The precipitated solid was collected by filtration to give 5-cyano-2-mercaptobenzoxazole (5.62 g) as a gray powder.

1. temperatureThe mixture was refluxed for 2 hr
2. temperatureto cool
3. additionwas added
4. filtrationThe precipitated solid was collected by filtration