HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1-Chloroethyl)-1,4-dimethylbenzene → 2-(1-[2,5-dimethylphenyl]-ethylthio)pyridine N-oxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1-Chloroethyl)-1,4-dimethylbenzene | HCID 93700 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | HCID 178526253 | HCID 178526253 | — |
| Product | 2-(1-[2,5-dimethylphenyl]-ethylthio)pyridine N-oxide | HCID 501135 | 83% |
Reaction Steps
The intermediate 2-(1-[2,5-dimethylphenyl]-ethylthio)pyridine N-oxide is prepared from 1-(2,5-dimethylphenyl)ethyl chloride and 2-mercaptopyridine N-oxide, sodium salt by the procedure described in U.S. Pat. No. 3,960,542, Example 2. Melting point 118°–120° C. Structure confirmed by IR and NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07064139B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-8906956420494eb780cded7bc3eddb04 |
| Source note | uspto-grants-2006_06 |