Pyrrolidine → HCID 9837724, compound
Reaction equation
C([O:8][C:9]1[CH:17]=[CH:16][CH:15]=[C:14]2[C:10]=1[CH:11]=[C:12]([C:19]([OH:21])=O)[N:13]2[CH3:18])C1C=CC=CC=1.[NH:22]1[CH2:26][CH2:25][CH2:24][CH2:23]1>>[OH:8][C:9]1[CH:17]=[CH:16][CH:15]=[C:14]2[C:10]=1[CH:11]=[C:12]([C:19]([N:22]1[CH2:26][CH2:25][CH2:24][CH2:23]1)=[O:21])[N:13]2[CH3:18]Participants
3
Procedure
From 4-benzyloxy-1-methyl-1H-indole-2-carboxylic acid and pyrrolidine the title compound was prepared by a method analogous to that described in Example 11. MS ES (M++H)=245.
Sources & evidence
- ORD record
- ord-4c4fbc8835f4487c9f5ba8d60709b2d4
- Source dataset
- uspto-grants-2006_06
- Patent number
- US07064143B1
Reaction notes
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