HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Diaminotoluene → HCID 178423472, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Diaminotoluene | HCID 10332 | — |
| Reactant | 5-chloro-1H-indazole-3-carbaldehyde | HCID 178520029 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 178423472 | HCID 178423472 | — |
Reaction Conditions
| Temperature | 100 °C |
|---|
Reaction Steps
A flask was charged with 5-chloro-1H-indazole-3-carbaldehyde (1.0 equivalent) and 3,4-diaminotoluene (1.0 equivalent) in toluene and ethanol (approximately 3:1). The flask was heated to 100° C. for 18 hours. The solvent was evaporated, and the residue purified by reverse phase HPLC to provide the desired product as a white solid. LC/MS (m/z) 283.1 (MH+), Rt 2.5 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07064215B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-3fdf0608cb4e4c9c9f40fa57e4465e2d |
| Source note | uspto-grants-2006_06 |