HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinemethanamine → 10-(Methoxycarbonyl)-N-(pyridin-3-ylmethyl)-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinemethanamine | HCID 31018 | — |
| Reactant | 10-(methoxycarbonyl)-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxylic acid | HCID 21947773 | — |
| Product | 10-(Methoxycarbonyl)-N-(pyridin-3-ylmethyl)-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxamide | HCID 22053652 | — |
Reaction Steps
The title compound was prepared by coupling the 10-(methoxycarbonyl)-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxylic acid of Step A with 3-(aminomethyl)pyridine (1.2 equiv.), in the manner of Example 1, Step G.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07064120B2 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-47fcde63104b4b9c8aa12e05c304571d |
| Source note | uspto-grants-2006_06 |