HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 2-amino-1-benzooxazol-2-yl-butan-1-one TFA salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | [1-(Benzooxazol-2-yl-hydroxy-methyl)-propyl]-carbamic acid tert-butyl ester | HCID 21031071 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-amino-1-benzooxazol-2-yl-butan-1-one TFA salt | HCID 86611131 | — |
Reaction Steps
[1-(Benzooxazol-2-yl-hydroxy-methyl)-propyl]-carbamic acid tert-butyl ester (275 mg, 0.89 mmol) and MeCl2 (5 ml) were mixed and TFA (1 ml) was added at room temperature. After stirring for 1 hour, the solvent and excess TFA were removed under vacuum to produce 260 mg of 2-amino-1-benzooxazol-2-yl-butan-1-one TFA salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07064123B1 |
| Source dataset | uspto-grants-2006_06 |
| ORD ID | ord-98dfa42e137d4fa58414dac727e9c6a5 |
| Source note | uspto-grants-2006_06 |